PUBLICATIONS

Complete list of publications at GoogleScholar

2024

Kimmel[JW1]  BR, Arora K, Chada NC, Bharti V, Kwiatkowski AJ, Finkelstein J, Hanna A, Arner EN, Sheehy TS, Pastora LE, Yang J, Pagendarm HM, Stone PT, Hargrove-Wiley E, Taylor BC, Hubert L, Fingleton BM, Gibson-Corley KN, May JC, McLean JA, Rathmell JC, Richmond A, Rathmell WK, Balko JM, Wilson JT*. Programable Albumin-Hitchhiking Nanobodies Enhance the Delivery of STING Agonists to Potentiate Cancer Immunotherapy. Preprint available here.

Sheehy TL, Kwiatkowski AJ, Arora K, Kimmel BR, Schulman JA, Gibson-Corley KN, Wilson JT*. STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy. ACS Central Science. 9:1765-1781 (2024).

Chada N, Wilson JT*. Jump-Starting CAR-T Cells to Go the Extra Mile with Nanotechnology. Current Opinion in Biotechnology. 8:103179 (2024).

Heintzman DR, Smith RC, Fisher EL, Ye X, Patterson AR, Elasy JH, Voss K, Chi C, Sugiura A, Rodriguez GJ, Chowdhury NU, Arner EN, Krystoviak ES, Mason FM, Steiner KK, Khan W, Olson LM, Jones AL, Hong HS, Bass L, Beier KL, Deng W, Lyssiotis CA, Newcomb DC, Bick AG, Rathmell WK, Wilson JT, Rathmell JC. Subset-specific mitochondrial and DNA damage shapes T cell responses to fever and inflammation. Science Immunology. 9:eadp3475 (2024)

Wescott E, Sun X, Gonzalez-Ericsson, Hanna A, Taylor B, Sanchez V, Bronzini J, Opalenik S, Sanders M, Wulfkule J, Gallagher R, Gomez H, Isaacs C, Bharti V, Wilson JT, Ballinger T, Santa-Maria C, Shah P, Dees E, Lehmann B, Abramson V, Hirst G, Brown-Swigart L, Esserman L, Petricoin E, Pietenpol J, Balko JM. Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer. Cancer Research Communications. 4:1120-1134 (2024).

Pastora LE, Namburu NS, Arora K, Christov PP, Wilson JT*. STING-Pathway Inhibiting Nanoparticles (SPINs) as a Platform for Treatment of Inflammatory Diseases. ACS Applied Bio Materials. 7:4867-4878 (2024).

Wilson JT*. Controlling the STING Pathway to Improve Immunotherapy. Nature Nanotechnology. 19: 718-720 (2024).

von Lersner AK, Fernandes FCL, Ozawa PMM, Jackson M, Masureel M, Ho H, Lima SM, Vagner T, Sung BW, Wehbe M, Franze K, Pua H, Wilson JT, Irish JM, Weaver AM, Di Vizio D, Zijlstra A. Multi-parametric Single-vesicle Flow Cytometry Resolves Extracellular Vesicle Heterogeneity and Reveals Selective Regulation of Biogenesis and Cargo Distribution. ACS Nano. 18: 10464-10484 (2024).

Wang-Bishop L#, Wehbe M#, Pastora LE#, Yang J, Kimmel BR, Garland KM, Becker KW, Carson CS, Gibson-Corley KN, Ulkoski D, Krishnamurthy V, Fedorova O, Richmond A, Pyle AM, Wilson JT*. Nanoparticle Retinoic Acid-Inducible Gene I Agonist for Cancer Immunotherapy. ACS Nano. 18: 11631-11643 (2024).

Palmer CR, Pastora LE, Kimmel BR, Pagendarm HM, Kwiatkowski AJ, Stone PT, Arora K, Francini N, Fedorova O, Pyle AM, Wilson JT*. Covalent Polymer-RNA Conjugates for Potent Activation of the RIG-I Pathway. Advanced Healthcare Materials. e2303815 (2024).

Baljon JJ, Kwiatkowski AJ, Pagendarm HM, Stone PT, Kumar A, Bharti V, Schulman JA, Becker KW, Stone PT, Roth EW, Christov PP, Joyce S, Wilson JT*. A Cancer Nanovaccine for Co-Delivery of Peptide Neoantigens and Optimized Combinations of STING and TLR4 Agonists ACS Nano. 18: 6845-6862 (2024).

2023

Jimenez L, Barman B, Jun YJ, Cocozza L, Krystofiak E, Saffold C, Vickers K, Wilson JT, Dawson T, Weaver A. Culture Conditions Greatly Impact the Levels of Vesicular and Extravesicular Ago2 and RNA in Extracellular Vesicle Preparations. Journal of Extracellular Vesicles. 12:e12366 (2023).

Pagendarm HM#, Stone PT#, Kimmel BR, Baljon JJ, Aziz M, Pastora LE, Hubert L, Roth E, Almunif S, Scott EA, Wilson JT*. Engineering Endosomolytic Nanocarriers of Diverse Morphology Using Confined Impingement Jet Mixing. Nanoscale. 15: 16016-16029 (2023).

Garland K#, Kwiatkowski A#,Tossberg JT, Crooke PS, Aune TM*, Wilson JT*. Nanoparticle Delivery of Immunostimulatory Alu RNA for Cancer Immunotherapy. Cancer Research Communications. 3: 1800-1809 (2023).

Wang-Bishop L#, Kimmel BR#, Ngwa VM, Madden MZ, Baljon JJ, Florian DC, Hanna A, Pastora LE, Sheehy TL, Kwiatkowski AJ, Wehbe M, Wen X, Becker KW, Garland KM, Schulman JA, Shae D, Edwards D, Wolf MM, Delapp R, Christov PP, Beckermann KE, Balko JM, Rathmell WK, Rathmell JC, Chen J, Wilson JT*. STING-Activating Nanoparticles Normalize the Vascular-Immune Interface to Potentiate Cancer Immunotherapy. Science Immunology. 8: eadd1153 (2023).

Florian, D. C., Bennett, N. E., Odziomek, M., Baljon, J. J., Wehbe, M., Merkel, A. R., … & Wilson, J. T. (2023). Nanoparticle STING Agonist Reprograms the Bone Marrow to an Antitumor Phenotype and Protects Against Bone Destruction. Cancer Research Communications, 3(2), 223-234.

2022

De Mel J, Hossain M, Shofolawe-Bakare O, Mohammad SA, Rasmussen E, Milloy K, Shields M, Roth EW, Arora K, Cueto R, Tang S-C, Wilson JT, Smith AE, Werfel TA. Dual-Responsive Glycopolymers for Intracellular Codelivery of Antigen and Lipophilic Adjuvants. Molecular Pharmaceutics. 19: 4705-4716 (2022).

Suryadevara N, Kumar A, Ye X, Rogers M, Williams JV, Wilson JT, Karijolich J, Joyce S. A Molecular Signature of Lung-Resident CD8+ T Cells Elicited by Subunit Vaccination. Scientific Reports. 12:19101 (2022).

Taylor D, Meyer CT, Sen R, Fu J, Tran E, Mirza B, Rodriguez G, Lang C, Feng H, Quarant V, Wilson JT, Kim YJ, Korrer M. MuSyC Dosing of Adjuvanted Cancer Vaccines Optimizes Antitumor Responses. Frontiers in Immunology. 13:936129 (2022).

Baljon JJ, Wilson JT.* Bioinspired Vaccines to Enhance MHC Class I Antigen Cross-Presentation. Current Opinion in Immunology. 77:102215 (2022).

Carson CS, Becker KW, Garland KM, Pagendarm HM, Stone PT, Arora K, Wang-Bishop L, Baljon JJ, Cruz LD, Joyce S, Wilson JT*. A Nanovaccine for Enhancing Cellular Immunity via Cytosolic Co-Delivery of Antigen and PolyIC RNA. Journal of Controlled Release. 345:354-370 (2022).

Garland KM, Sheehy TL, Wilson JT*. Chemical Strategies for STING Pathway Activation in Cancer Immunotherapy. Chemical Reviews. 122:5977-6039 (2022).

Sharma J, Carson CS, Douglas T*, Wilson JT*, Joyce S*. (2022) “Nano-Particulate Platforms for Vaccine Delivery to Enhance Antigen-Specific CD8+ T Cell Response.” In: Thomas S (eds) Vaccine Design. Methods in Molecular Biology, v2412. Humana, New York, NY.

2021

Garland KM, Rosch JC, Carson CS, Wang-Bishop L, Hanna A, Sevimli S, Van Kaer C, Balko JM, Ascano M, Wilson JT*. Pharmacological Activation of cGAS for Intratumoral Immunotherapy. Frontiers in Immunology. 12:753472 (2021).

Wilson JT*, Lund AW*. Building New Roads to Stronger Immunity. Science Advances. 7(13):eabh3971 (2021).

Munson MJ, O’Driscoll G, Silva AM, Lazaro-Ibanez E, Gallud A, Wilson JT, Collen A, Esbjorner EK, Sabirsh A. A High-Throughput Galectin-9 Imaging Assay for Quantifying Nanoparticle Uptake, Endosomal Escape and Functional RNA Delivery. Communications Biology. 4:211 (2021).

Ulkoski D, Munson M, Jacobson ME, Palmer CR, Carson CS, Sabirsh A, Wilson JT, Krishnamurthy VR. High-Throughput Automation of Endosomolytic Polymers for mRNA Delivery. ACS Applied Biomaterials. 4:1640-1654 (2021).

Knight FC, Wilson JT*. Engineering Vaccines for Tissue-Resident Memory T Cells. Advanced Therapeutics. 4:2000230 (2021).

Nguyen DC#, Shae D#, Pagendarm H, Becker KW, Wehbe M, Kilchrist K, Pastora LE, Palmer CR, Seber P, Christov PP, Duvall CL, Wilson JT*. Amphiphilic Polyelectrolyte Graft Copolymers Enhance the Activity of Cyclic Dinucleotide STING Agonists. Advanced Healthcare Materials 10(2):e2001056 (2021).

Wehbe M, Wang-Bishop L, Becker KW, Shae D, Baljon JJ, He X, Christov PP, Boyd KL, Wilson JT*. Nanoparticle Delivery Improves the Pharmacokinetic Properties of Cyclic Dinucleotide STING Agonists to Open a Therapeutic Window for Intravenous Administration. Journal of Controlled Release. 330: 1118-1129 (2021).

2020

Jacobson ME#, Becker KW#, Pastora LE, Palmer CR, Fletcher RB, Colins KA, Baljon JJ, Fedorova O, Duvall CL, Pyle AM, Wilson JT*. Structural Optimization of Polymeric Carriers to Enhance the Immunostimulatory Activity of Molecularly-Defined RIG-I Agonists. ACS Central Science. 6:2008 (2020).

Kumar A, Suryadevara N, Wolf K, Wilson JT, DiPaolo RJ, Brien JD, Joyce S. Characterization of HLA-B*07:02-restricted Epitopes Recognized by Ectromelia Virus-Specific CD8+ T Cells. Scientific Reports. 10:13167 (2020).

Shae D#, Baljon JJ#, Wehbe M, Cristov P, Becker KW, Kumar A, Suryadevara N, Carson C, Palmer C, Knight FC, Joyce S, Wilson JT*. Co-Delivery of Peptide Neoantigens and Stimulator of Interferon Genes Agonists with Enhances Response to Cancer Vaccines. ACS Nano. 14: 9904-9916 (2020).

Wang-Bishop L, Wehbe M, Shae D, James JL, Hacker B, Garland KM, Christov P, Rafat M, Balko JM, Wilson JT*. Potent STING Activation Stimulates Immunogenic Cell Death to Enhance Antitumor Immunity in Neuroblastoma. Journal for ImmunoTherapy of Cancer. 8:e000282 (2020).

Ou YC, Wen X, Johnson CA, Shae D, Ayala OD, Webb JA, Lin EC, DeLapp RC, Boyd KL, Richmond A, Mahadeven-Jansen A, Rafat M, Wilson JT, Balko JM, Tantaway MN, Vilgelm AE, Bardhan R. Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies. ACS Nano. 14:651-663 (2020).

2019

Knight FC, Gilchuk P, Kumar A, Becker KW, Sevimli S, Jacobson ME, Suryadevara N, Wang-Bishop L, Boyd KL, Crowe JE, Joyce S, Wilson JT*. Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells. ACS Nano. 13:10939-10960 (2019).

Shae D#, Baljon JJ#, Wehbe M, Becker KW, Sheehy TL, Wilson JT*. At the Bench: Engineering the Next Generation of Cancer Vaccines. Journal of Leukocyte Biology. doi:10.1002/JLB.5BT0119-016R (2019).

Ulkoski D, Bak A, Wilson JT, Krishnamurthy VR. Recent Advances in Polymeric Nanoparticles for the Delivery of RNA Therapeutics. Expert Opinion on Drug Delivery 16:1149-1167 (2019).

Garland KM, Sevimli S, Kilchrist KV, Duvall CL, Cook RS, Wilson JT*. Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles. Cellular and Molecular Bioengineering 12: 429-442 (2019).

Shae D, Becker KW, Chistov P, Yun D-S, Lytton-Jean A, Sevimli S, Ascano M, Kelley M, Johnson D, Balko J, Wilson JT*. Endosomolytic Polymersomes Increase the Activity of Cyclic Dinucleotide STING Agonists to Enhance Cancer Immunotherapy. Nature Nanotechnology 14: 269-278 (2019).

Baljon JJ, Dandy A, Wang-Bishop L, Wehbe M, Jacobson ME, Wilson JT*. The Efficiency of Cytosolic Drug Delivery Using pH-Responsive Endosomolytic Polymers Does Not Correlate with Activation of the NPRP3 Inflammasome. Biomaterials Science 7:1888-1897 (2019).

Wilson JT*. A Sweeter Approach to Vaccine Design. Science. 363:584-585 (2019).

Jacobson ME, Wang-Bishop L, Becker KW, Wilson JT*. Delivery of 5’-Triphosphate RNA with Endosomolytic Nanoparticles Potently Activates RIG-I to Improve Cancer Immunotherapy. Biomaterials Science. 7:547-559 (2019).

2018

Elion D, Jacobson ME, Hicks D, Rahman B, Sanchez V, Gonzalez-Ericsson P, Fedorova P, Pyle A, Wilson JT, Cook RS. Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers. Cancer Research.  78:6183-6195 (2018).

Qiu F, Becker KW, Knight FC, Baljon JJ, Shae D, Gilchuk P, Joyce S, Wilson JT*. Poly(propylacrylic acid)-Peptide Nanoplexes as a Platform for Enhancing the Immunogenicity of Neoantigen Cancer Vaccines. Biomaterials.182:82-91 (2018).

Palmer CR, Jacobson ME, Fedorova O, Pyle AM, Wilson JT*. Environmentally Triggerable RIG-I Agonists Using Synthetic Polymer Overhangs. Bioconjugate Chemistry. 29:742-747 (2018).

2017

Sevimli S, Knight F, Gilchuk P, Joyce S, Wilson JT*. Fatty Acid-Mimetic Micelles for Dual-Delivery of Antigens and Imidazoquinoline Adjuvants. ACS Biomaterials Science & Engineering 3:179-194 (2017).

Gilchuk P, Knight FC, Wilson JT, Joyce S. (2017) “Eliciting Epitope-Specific CD8 T Cell Response by Immunization with Microbial Proteinantigens Formulated With Alpha-Galactosylceramide: Theory, Practice, & Protocols.” In C.B. Fox ed. Methods in Molecular Biology: Vaccine Adjuvants — Methods and Protocols. New York, NY: Springer Science & Business Media, LLC.

2016

Ou Y-C, Webb JA, Faley S, Shae D, Talbert EM, Lin S, Cutright C, Wilson JT, Bellan LM, Bardhan R. Gold Nanoantenna-Mediated Photothermal Drug Delivery from Thermosensitive Liposomes in Breast Cancer. ACS Omega 1:234-243 (2016).

Shae D, Postma A*, Wilson JT*. Vaccine Delivery: Where Polymer Chemistry Meets Immunology. Ther Deliv. 7:193-6 (2016).

Graham DJ, Wilson JT, Lai JJ, Stayton PS, Castner DG. 3D localization of polymer nanoparticles in cells using ToF-SIMS. Biointerphases 11:02A304 (2016).

2015

Gilchuk P, Hill TM, Wilson JT, Joyce S. Discovering Protective CD8 T Cell Epitopes – No Single Immunologic Property Predicts It! Current Opinion in Immunology 34:43-51 (2015).

Wilson JT#, Postma A#, Keller S, Convertine AJ, Moad G, Rizzardo E, Chiefari J, Stayton PS. Enhancement of MHC-I Antigen Presentation via Architectural Control of pH-responsive Endosomolytic Polymer Nanoparticles. The AAPS Journal 17:358-369 (2015).

Complete list of publications at GoogleScholar